Cell Line Marker
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Cell lines are cultured cells derived from primary cells or tissues that have the ability to proliferate and be maintained in the laboratory. They serve as valuable tools for studying specific cell types and their functions. Antibody markers are commonly used to identify and characterize these cell lines based on the expression of specific proteins. The Jurkat is a widely studied human T-cell leukemia cell line. In Jurkat cells, the expression of CD3 and CD4 confirms their T-cell lineage, while CD45 serves as a general leukocyte marker. These antibody markers aid in distinguishing Jurkat cells from other cell types and investigating T-cell-specific processes. HEK293 (Human Embryonic Kidney 293) on the other hand is a popular cell line derived from human embryonic kidney cells. It can be characterized using antibody markers such as GAPDH (glyceraldehyde 3-phosphate dehydrogenase), which is commonly used as a loading control in protein analysis, or specific markers like HEK293-EBNA1, indicating the presence of the Epstein-Barr nuclear antigen 1 used for stable gene expression. Overall, the use of antibody markers in characterizing cell lines ensures their authenticity and aids in understanding their biological properties and applications in research. antibodies-online offers a broad range of cell line markers, discover different cell lines and their antibody markers on the left.
