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ARL6 Products

(ADP Ribosylation Factor Like GTPase 6 (ARL6))

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The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are important regulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomic sequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-back communication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this protein suggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008].

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Featured ARL6 Categories

ARL6 Antibodies

High quality antibodies with extensive validation data.

ARL6 ELISA Kits

Reliable ELISA kits for a wide range of species.

ARL6 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended ARL6 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC, WB
Validations
  • (5)
Cat. No. ABIN6137113
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application IHC
Validations
  • (4)
Cat. No. ABIN7264305
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (4)
  • (2)
Cat. No. ABIN1882064
Quantity 400 μL
Datasheet Datasheet

Recommended ARL6 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1742694
Quantity 96 tests
Datasheet Datasheet
Reactivity Sheep
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1773598
Quantity 96 tests
Datasheet Datasheet
Reactivity Pig
Analytical Method
Validations
Cat. No. ABIN1750023
Quantity 96 tests
Datasheet Datasheet

Recommended ARL6 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN667468
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7288757
Quantity 200 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345622
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our ARL6 products

Wiens, Tong, Esmail, Oh, Gerdes, Wang, Tempel, Rattner, Katsanis, Park, Leroux: "Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling." in: The Journal of biological chemistry, Vol. 285, Issue 21, pp. 16218-30, (2010) (PubMed).

Chiang, Nishimura, Searby, Elbedour, Carmi, Ferguson, Secrist, Braun, Casavant, Stone, Sheffield: "Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3)." in: American journal of human genetics, Vol. 75, Issue 3, pp. 475-84, (2004) (PubMed).

Fan, Esmail, Ansley, Blacque, Boroevich, Ross, Moore, Badano, May-Simera, Compton, Green, Lewis, van Haelst, Parfrey, Baillie, Beales, Katsanis, Davidson, Leroux: "Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome." in: Nature genetics, Vol. 36, Issue 9, pp. 989-93, (2004) (PubMed).

Pasqualato, Renault, Cherfils: "Arf, Arl, Arp and Sar proteins: a family of GTP-binding proteins with a structural device for 'front-back' communication." in: EMBO reports, Vol. 3, Issue 11, pp. 1035-41, (2002) (PubMed).

Ingley, Williams, Walker, Tsai, Colley, Sayer, Tilbrook, Sarna, Beaumont, Klinken: "A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit." in: FEBS letters, Vol. 459, Issue 1, pp. 69-74, (1999) (PubMed).

Jacobs, Schilf, Fliegert, Koling, Weber, Schürmann, Joost: "ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal." in: FEBS letters, Vol. 456, Issue 3, pp. 384-8, (1999) (PubMed).

Synonyms and alternative names related to ARL6

ADP ribosylation factor like GTPase 6 (ARL6), ADP-ribosylation factor-like 6 (Arl6), ADP-ribosylation factor like GTPase 6 (Arl6), ADP-ribosylation factor-like 6 (arl6), ADP-ribosylation factor-like protein 6 (arl-6), ADP ribosylation factor like GTPase 6 L homeolog (arl6.L), 1110018H24Rik, 2210411E14Rik, arl6, BBS3, RP55, zgc:101762

Protein level used designations for ARL6

  • ADP-ribosylation factor-like protein 6
  • Bardet-Biedl syndrome 3 protein
  • ADP-ribosylation-like 6
  • ADP-ribosylation-like factor homolog ARL6
  • bbs3
  • ADP ribosylation factor like GTPase 6 L homeolog
  • ADP-ribosylation factor-like 6
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