ARHGEF7 Products
(rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))
Categories
Rho GTPases play a fundamental role in numerous cellular processes triggered by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. This protein can induce membrane ruffling. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].
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Featured ARHGEF7 Categories
ARHGEF7 Antibodies
High quality antibodies with extensive validation data.
ARHGEF7 ELISA Kits
Reliable ELISA kits for a wide range of species.
ARHGEF7 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ARHGEF7 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7240553
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, ICC
Validations
- (1)
- (1)
Cat. No.
ABIN1169227
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IP, IF
Validations
- (2)
Cat. No.
ABIN7167994
Quantity
100 μg
Datasheet
Datasheet
Recommended ARHGEF7 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6959165
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674757
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5674758
Quantity
96 tests
Datasheet
Datasheet
Recommended ARHGEF7 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7124865
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345566
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7399892
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our ARHGEF7 products
: "Sorting nexin 27 protein regulates trafficking of a p21-activated kinase (PAK) interacting exchange factor (β-Pix)-G protein-coupled receptor kinase interacting protein (GIT) complex via a PDZ domain ..." in: The Journal of biological chemistry, Vol. 286, Issue 45, pp. 39403-16, (2011) (PubMed).: "Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling." in: The Journal of cell biology, Vol. 145, Issue 4, pp. 851-63, (1999) (PubMed).
: "A novel regulator of p21-activated kinases." in: The Journal of biological chemistry, Vol. 273, Issue 37, pp. 23633-6, (1998) (PubMed).
: "PAK kinases are directly coupled to the PIX family of nucleotide exchange factors." in: Molecular cell, Vol. 1, Issue 2, pp. 183-92, (1998) (PubMed).
: "Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion." in: Biochemical and biophysical research communications, Vol. 235, Issue 3, pp. 794-8, (1997) (PubMed).
Synonyms and alternative names related to ARHGEF7
Rho guanine nucleotide exchange factor 7 (ARHGEF7), Rho guanine nucleotide exchange factor 7 S homeolog (arhgef7.S), Rho guanine nucleotide exchange factor 7 (arhgef7), ankyrin repeat domain 10 (ANKRD10), Rho guanine nucleotide exchange factor 7 (Arhgef7), Rho guanine nucleotide exchange factor (GEF7) (Arhgef7), Rho guanine nucleotide exchange factor (GEF) 7b (arhgef7b), ARHGEF7, arhgef7, bbh, BETA-PIX, betaPix, betaPix-b, betaPix-c, bpix, Cool, COOL-1, cool-1, COOL1, cool1, im:7142367, mKIAA0142, Nbla10314, P50, p50, P50BP, P85, p85, P85COOL1, p85Cool1, P85SPR, P85spr, p85SPR, PAK3, pak3, Pak3bp, PIX, PIXB, pixb, wu:fc35h08, zgc:101775Protein level used designations for ARHGEF7
- PAK-interacting exchange factor beta
- SH3 domain-containing proline-rich protein
- guanine nucleotide exchange factor 7
- rho guanine nucleotide exchange factor 7
- Rho guanine nucleotide exchange factor (GEF) 7
- Rho guanine nucleotide exchange factor 7
- rho guanine nucleotide exchange factor 7-like
- beta-Pix
- Pak interacting exchange factor
- Pak3 binding protein
- Rho guanine exchange factor betaPix
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