ARAP1 Products
(ArfGAP with RhoGAP Domain, Ankyrin Repeat and PH Domain 1 (ARAP1))
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The protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].
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Featured ARAP1 Categories
ARAP1 Antibodies
High quality antibodies with extensive validation data.
ARAP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended ARAP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IP, ICC
Validations
- (1)
- (2)
Cat. No.
ABIN302078
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
Cat. No.
ABIN7144564
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
ELISA, IHC, WB
Validations
- (2)
Cat. No.
ABIN185099
Quantity
100 μg
Datasheet
Datasheet
Recommended ARAP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345438
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345440
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3089102
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our ARAP1 products
: "ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5." in: Molecular biology of the cell, Vol. 23, Issue 13, pp. 2481-9, (2012) (PubMed).: "Arf and Rho GAP adapter protein ARAP1 participates in the mobilization of TRAIL-R1/DR4 to the plasma membrane." in: Apoptosis : an international journal on programmed cell death, Vol. 13, Issue 3, pp. 423-36, (2008) (PubMed).
: "Comparison of effects of PKA catalytic subunit on I(h) and calcium channel currents in rat dorsal root ganglion cells." in: Biomedical research (Tokyo, Japan), Vol. 28, Issue 4, pp. 177-89, (2007) (PubMed).
: "ARAP1: a point of convergence for Arf and Rho signaling." in: Molecular cell, Vol. 9, Issue 1, pp. 109-19, (2002) (PubMed).
: "cAMP-independent role of PKA in tonicity-induced transactivation of tonicity-responsive enhancer/ osmotic response element-binding protein." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16800-5, (2002) (PubMed).
Synonyms and alternative names related to ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (ARAP1), centaurin, delta 2 (centd2), ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 (Arap1), 2410002L19Rik, ARAP1, CENTD2, Centd2, Ci-ArfGAP-8, mKIAA0782Protein level used designations for ARAP1
- centaurin delta 2
- centaurin, delta 2
- ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
- arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
- centaurin-delta-2
- cnt-d2
- ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1
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