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APP Proteins

(Amyloid beta (A4) Precursor Protein (APP))
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
APP Protein (AA 18-669) (His tag) APP Protein (AA 18-669) (His tag) APP Protein (AA 18-669) (His tag) (ABIN7092740)

APP Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 90 % as determined by SDS-PAGE and Coomassie blue staining.

APP Protein (AA 19-305) (GST tag) APP Protein (AA 19-305) (GST tag) APP Protein (AA 19-305) (GST tag) (ABIN1345399)

APP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

APP Protein (AA 1-305) (GST tag) APP Protein (AA 1-305) (GST tag) APP Protein (AA 1-305) (GST tag) (ABIN1345401)

APP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

APP Proteins by Grade

Find APP Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

APP Proteins by Origin

Find APP Proteins for a variety of species such as anti-Human APP, anti-Mouse APP, anti-Rat APP. The species listed below are among those available. Click on a link to go to the corresponding products.

APP Proteins by Source

Here you will find APP Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

APP Proteins by Protein Type

Here you can find APP Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

APP Proteins by Application

Find APP Proteins validated for a specific application such as WB, SDS, Imm, PC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

APP Proteins by Biological Activity

Find APP Proteins with a specific Biological Activity. The Biological Activity listed below are among those available. Click on a link to go to the corresponding products.

Popular APP Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN7092740
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345399
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345401
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2714676
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN2127988
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392971
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423663
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7423672
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7392974
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7402439
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7400156
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7536320
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
Cat. No. ABIN7194239
Quantity 50 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3008253
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2714677
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our APP Proteins

Planque, Nishiyama, Sonoda, Lin, Taguchi, Hara, Kolodziej, Mitsuda, Gonzalez, Sait, Fukuchi, Massey, Friedland, ONuallain, Sigurdsson, Paul: "Specific amyloid β clearance by a catalytic antibody construct." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10229-41, (2015) (PubMed).

Yoshikai, Sasaki, Doh-ura, Furuya, Sakaki: "Genomic organization of the human amyloid beta-protein precursor gene." in: Gene, Vol. 87, Issue 2, pp. 257-63, (1990) (PubMed).

Lemaire, Salbaum, Multhaup, Kang, Bayney, Unterbeck, Beyreuther, Müller-Hill: "The PreA4(695) precursor protein of Alzheimer's disease A4 amyloid is encoded by 16 exons." in: Nucleic acids research, Vol. 17, Issue 2, pp. 517-22, (1989) (PubMed).

Ponte, Gonzalez-DeWhitt, Schilling, Miller, Hsu, Greenberg, Davis, Wallace, Lieberburg, Fuller: "A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors." in: Nature, Vol. 331, Issue 6156, pp. 525-7, (1988) (PubMed).

Kang, Lemaire, Unterbeck, Salbaum, Masters, Grzeschik, Multhaup, Beyreuther, Müller-Hill: "The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor." in: Nature, Vol. 325, Issue 6106, pp. 733-6, (1987) (PubMed).

Aliases for APP Proteins

amyloid beta precursor protein (APP) Proteins
amyloid beta (A4) precursor protein (APP) Proteins
amyloid beta precursor protein (app) Proteins
beta amyloid protein precursor-like (Appl) Proteins
amyloid beta precursor protein (App) Proteins
amyloid beta (A4) precursor protein (App) Proteins
amyloid beta (A4) precursor protein a (appa) Proteins
amyloid beta precursor protein L homeolog (app.L) Proteins
AAA Proteins
aaa Proteins
ABETA Proteins
abeta Proteins
Abeta Proteins
ABPP Proteins
abpp Proteins
Abpp Proteins
AD1 Proteins
ad1 Proteins
Adap Proteins
Ag Proteins
APP Proteins
app Proteins
APP-like Proteins
APPI Proteins
appi Proteins
APPL Proteins
appl Proteins
BcDNA:GH04413 Proteins
betaApp Proteins
CG7727 Proteins
CTFgamma Proteins
ctfgamma Proteins
CVAP Proteins
cvap Proteins
Cvap Proteins
Dmel\\CG7727 Proteins
E030013M08Rik Proteins
EG:65F1.5 Proteins
PN-II Proteins
PN2 Proteins
pn2 Proteins
wu:fj34d10 Proteins
wu:fk65e12 Proteins
zgc:85740 Proteins
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