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Apoptosis Protease Activating Factor 1 ELISA Kits

(Apoptosis Protease Activating Factor 1)
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Recommended Apoptosis Protease Activating Factor 1 ELISA Kits

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Reactivity Human
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Cat. No. ABIN6962035
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Cat. No. ABIN6964967
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Latest Publications for our Apoptosis Protease Activating Factor 1 products

Tang, Zhang, Chen, Xiang, Shen, Li: "The role of miR-19b in the inhibition of endothelial cell apoptosis and its relationship with coronary artery disease." in: Scientific reports, Vol. 5, pp. 15132, (2016) (PubMed).

Synonyms and alternative names related to Apoptosis Protease Activating Factor 1

apoptotic peptidase activating factor 1 (APAF1), APAF-1, CED4

Protein level used designations for Apoptosis Protease Activating Factor 1

  • apoptotic protease-activating factor 1
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