APOB Products
(Apolipoprotein B (APOB))
Categories
This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008].
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Featured APOB Categories
APOB Antibodies
High quality antibodies with extensive validation data.
APOB ELISA Kits
Reliable ELISA kits for a wide range of species.
APOB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended APOB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (10)
Cat. No.
ABIN7429130
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7426895
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, ICC, FACS
Validations
- (2)
- (4)
Cat. No.
ABIN968961
Quantity
100 μL
Datasheet
Datasheet
Recommended APOB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (5)
Cat. No.
ABIN6730915
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
- (1)
Cat. No.
ABIN612664
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6963642
Quantity
96 tests
Datasheet
Datasheet
Recommended APOB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121865
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7121866
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1345338
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our APOB products
: "Dietary fat induced chylomicron-mediated LPS translocation in a bicameral Caco-2cell model." in: Lipids in health and disease, Vol. 22, Issue 1, pp. 4, (2023) (PubMed).: "Blood concentrations of small extracellular vesicles are determined by a balance between abundant secretion and rapid clearance." in: Journal of extracellular vesicles, Vol. 9, Issue 1, pp. 1696517, (2020) (PubMed).
: "Murine Surf4 is essential for early embryonic development." in: PLoS ONE, Vol. 15, Issue 1, pp. e0227450, (2020) (PubMed).
: "A critical role of VMP1 in lipoprotein secretion." in: eLife, Vol. 8, (2020) (PubMed).
: "Acute whole apple consumption did not influence postprandial lipaemia: a randomised crossover trial." in: The British journal of nutrition, Vol. 123, Issue 7, pp. 807-817, (2020) (PubMed).
: "GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis." in: Cell, Vol. 179, Issue 6, pp. 1276-1288.e14, (2020) (PubMed).
: "Punicalagin Regulates Apoptosis-Autophagy Switch via Modulation of Annexin A1 in Colorectal Cancer." in: Nutrients, Vol. 12, Issue 8, (2020) (PubMed).
: "Gut-derived lipopolysaccharides increase post-prandial oxidative stress via Nox2 activation in patients with impaired fasting glucose tolerance: effect of extra-virgin olive oil." in: European journal of nutrition, Vol. 58, Issue 2, pp. 843-851, (2019) (PubMed).
: "Nuclear lipid droplets derive from a lipoprotein precursor and regulate phosphatidylcholine synthesis." in: Nature communications, Vol. 10, Issue 1, pp. 473, (2019) (PubMed).
: "Spontaneous severe hypercholesterolemia and atherosclerosis lesions in rabbits with deficiency of low-density lipoprotein receptor (LDLR) on exon 7." in: EBioMedicine, Vol. 36, pp. 29-38, (2019) (PubMed).
Synonyms and alternative names related to APOB
apolipoprotein B (APOB), apolipoprotein B (Apob), Ac1-060, AI315052, APOB, ApoB(100), ApoB-48, apob-48, Apo B-100, ApoB-100, apob-100, APOB-100, FLDB, LDLCQ4Protein level used designations for APOB
- apo B-100
- apoB-100
- apoB-48
- apolipoprotein B (including Ag(x) antigen)
- apolipoprotein B-100
- apolipoprotein B48
- mutant Apo B 100
- apolipoprotein B PI
- apolipoprotein B-48
- apolipoprotein B
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