APH1B Products
(Anterior Pharynx Defective 1 Homolog B (Aph1b))
Categories
This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein. [provided by RefSeq, Sep 2011].
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Featured APH1B Categories
APH1B Antibodies
High quality antibodies with extensive validation data.
APH1B Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended APH1B Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (1)
Cat. No.
ABIN7139847
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p), ICC
Validations
- (1)
Cat. No.
ABIN1386275
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA
Validations
Cat. No.
ABIN7139850
Quantity
100 μL
Datasheet
Datasheet
Recommended APH1B ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6976100
Quantity
96 tests
Datasheet
Datasheet
Recommended APH1B Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3104477
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3125756
Quantity
1 mg
Datasheet
Datasheet
Reactivity
C. elegans, Human, Mouse, Rat
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2747265
Quantity
5 applications
Datasheet
Datasheet
Latest Publications for our APH1B products
: "Nicastrin is required for APP but not Notch processing, while Aph-1 is dispensable for processing of both APP and Notch." in: Journal of neurochemistry, (2015) (PubMed).: "Impact of the cellular prion protein on amyloid-? and 3PO-tau processing." in: Journal of Alzheimer's disease : JAD, Vol. 38, Issue 3, pp. 551-65, (2013) (PubMed).
Synonyms and alternative names related to APH1B
aph-1 homolog B, gamma-secretase subunit (APH1B), aph-1 homolog B, gamma secretase subunit (Aph1b), aph1 homolog B, gamma secretase subunit (Aph1b), 2310057K14Rik, APH-1B, APH-1B', Aph1c, PRO1328, PSFL, TAAV688Protein level used designations for APH1B
- anterior pharynx defective 1 homolog B
- aph-1beta
- gamma-secretase subunit APH-1B
- anterior pharynx defective 1b homolog
- APH-1b
- APH1B homolog
- anterior pharynx defective 1c homolog
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