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APH1A Antibodies

(Anterior Pharynx Defective 1 Homolog A (C. Elegans) (APH1A))

Your search for reliable APH1A antibodies ends here. APH1A, known by aliases such as APH1A, aph1a.L, Aph1a, LOC100219182, is an integral part of our antibody range. Whether you're working with Human, Mouse, Rat, Cow, Dog, or other species, our range of APH1A antibodies offer precise detection across diverse samples. These specialized antibodies are tailored for various scientific applications like WB, ELISA, FACS, IF (cc), IF (p), providing you with options like polyclonal, recombinant, and monoclonal antibodies, sourced from different host species such as Rabbit, Goat. The efficacy of our antibodies is well-established, demonstrated through multiple methods.

Detailed information, including references, images, and validations by other customers, can be found on each product page. Should you require assistance in finding a specific product, our customer service team is ready to assist. Utilize our APH1A antibodies in your research endeavors for dependable APH1A detection.

APH1A antibody  (AA 71-170) APH1A antibody  (AA 71-170) APH1A antibody (AA 71-170) (ABIN706016)

APH1A Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

APH1A antibody  (Internal Region) APH1A antibody  (Internal Region) APH1A antibody (Internal Region) (ABIN190762)

Verified APH1A Reactivity: Human WB, ELISA, IHC Host: Goat Polyclonal unconjugated

APH1A antibody  (N-Term) APH1A antibody  (N-Term) APH1A antibody (N-Term) (ABIN390272)

APH1A Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal RB4994 unconjugated

APH1A Antibodies by Grade

Find APH1A Antibodies with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Reactivity

Find APH1A Antibodies for a variety of species such as anti-Human APH1A, anti-Mouse APH1A, anti-Rat APH1A. The species listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Application

Find APH1A Antibodies validated for a specific application such as WB, ELISA, FACS, IF (cc). Some of the available applications are listed below. Click on a link to go to the corresponding products.

APH1A Antibodies by Host

Find APH1A Antibodies with a specific Host. The Host listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Binding Specificity

Find APH1A Antibodies with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Clonality

Find available monoclonal or polyclonal APH1A Antibodies. Click on a link to go to the corresponding products.

APH1A Antibodies by Clone

Find APH1A Antibodies with a specific Clone. The Clone listed below are among those available. Click on a link to go to the corresponding products.

APH1A Antibodies by Conjugate

Find APH1A Antibodies with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular APH1A Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
Cat. No. ABIN706016
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN190762
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN390272
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (2)
Cat. No. ABIN7265628
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7153559
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB
Validations
  • (1)
Cat. No. ABIN1539365
Quantity 400 μL
Datasheet Datasheet
Reactivity Cow, Dog, Horse, Human, Monkey, Opossum
Application WB
Validations
  • (1)
Cat. No. ABIN960079
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p), EIA
Validations
  • (2)
Cat. No. ABIN499309
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application
Validations
Cat. No. ABIN7153561
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7153562
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA
Validations
Cat. No. ABIN7153560
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
Cat. No. ABIN7094535
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN706018
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN883018
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, FACS, IF (cc), IF (p)
Validations
Cat. No. ABIN2809828
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our APH1A Antibodies

Area-Gomez, de Groof, Boldogh, Bird, Gibson, Koehler, Yu, Duff, Yaffe, Pon, Schon: "Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria." in: The American journal of pathology, Vol. 175, Issue 5, pp. 1810-6, (2009) (PubMed).

Spasic, Raemaekers, Dillen, Declerck, Baert, Serneels, Füllekrug, Annaert: "Rer1p competes with APH-1 for binding to nicastrin and regulates gamma-secretase complex assembly in the early secretory pathway." in: The Journal of cell biology, Vol. 176, Issue 5, pp. 629-40, (2007) (PubMed).

Ma, Li, Price, Wong: "APH-1a is the principal mammalian APH-1 isoform present in gamma-secretase complexes during embryonic development." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 1, pp. 192-8, (2005) (PubMed).

Periz, Fortini: "Functional reconstitution of gamma-secretase through coordinated expression of presenilin, nicastrin, Aph-1, and Pen-2." in: Journal of neuroscience research, Vol. 77, Issue 3, pp. 309-22, (2004) (PubMed).

Takasugi, Tomita, Hayashi, Tsuruoka, Niimura, Takahashi, Thinakaran, Iwatsubo: "The role of presenilin cofactors in the gamma-secretase complex." in: Nature, Vol. 422, Issue 6930, pp. 438-41, (2003) (PubMed).

Marlow, Canet, Haugabook, Hardy, Lahiri, Sambamurti: "APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity." in: Biochemical and biophysical research communications, Vol. 305, Issue 3, pp. 502-9, (2003) (PubMed).

Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Gu, Chen, Sanjo, Kawarai, Hasegawa, Duthie, Li, Ruan, Luthra, Mount, Tandon, Fraser, St George-Hyslop: "APH-1 interacts with mature and immature forms of presenilins and nicastrin and may play a role in maturation of presenilin.nicastrin complexes." in: The Journal of biological chemistry, Vol. 278, Issue 9, pp. 7374-80, (2003) (PubMed).

Goutte, Tsunozaki, Hale, Priess: "APH-1 is a multipass membrane protein essential for the Notch signaling pathway in Caenorhabditis elegans embryos." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 2, pp. 775-9, (2002) (PubMed).

Aliases for APH1A Antibodies

aph-1 homolog A, gamma-secretase subunit (APH1A) Antibodies
aph-1 homolog A, gamma secretase subunit L homeolog (aph1a.L) Antibodies
aph-1 homolog A, gamma secretase subunit (Aph1a) Antibodies
anterior pharynx defective 1 homolog A (C. elegans) (APH1A) Antibodies
aph1 homolog A, gamma secretase subunit (Aph1a) Antibodies
acylamino-acid-releasing enzyme-like (LOC100219182) Antibodies
6530402N02Rik Antibodies
APH-1 Antibodies
APH-1A Antibodies
APH-1a Antibodies
CGI-78 Antibodies
RGD1311546 Antibodies
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