APCS Products
(Amyloid P Component, Serum (APCS))
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The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008].
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Featured APCS Categories
APCS Antibodies
High quality antibodies with extensive validation data.
APCS ELISA Kits
Reliable ELISA kits for a wide range of species.
APCS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended APCS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7438559
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7433756
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (6)
Cat. No.
ABIN3022714
Quantity
100 μL
Datasheet
Datasheet
Recommended APCS ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (4)
- (1)
Cat. No.
ABIN6953696
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6953697
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN7041556
Quantity
96 tests
Datasheet
Datasheet
Recommended APCS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275545
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275546
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
- (1)
Cat. No.
ABIN7538131
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our APCS products
: "Amniotic fluid pentraxins: Potential early markers for identifying intra-amniotic inflammatory complications in preterm pre-labor rupture of membranes." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 79, Issue 5, pp. e12789, (2019) (PubMed).: "Identification of candidate biomarkers for hepatocellular carcinoma in plasma of HCV-infected cirrhotic patients by 2-D DIGE." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 34, Issue 3, pp. 438-46, (2015) (PubMed).
: "Efficient amyloid A clearance in the absence of immunoglobulins and complement factors." in: The American journal of pathology, Vol. 182, Issue 4, pp. 1297-307, (2013) (PubMed).
: "Cefditoren and ceftriaxone enhance complement-mediated immunity in the presence of specific antibodies against antibiotic-resistant pneumococcal strains." in: PLoS ONE, Vol. 7, Issue 9, pp. e44135, (2012) (PubMed).
: "Combined proteomic and metabolomic profiling of serum reveals association of the complement system with obesity and identifies novel markers of body fat mass changes." in: Journal of proteome research, Vol. 10, Issue 10, pp. 4769-88, (2011) (PubMed).
: "Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes." in: PLoS ONE, Vol. 6, Issue 6, pp. e21226, (2011) (PubMed).
: "Circulation levels of acute phase proteins in patients with Takayasu arteritis." in: Journal of vascular surgery, Vol. 51, Issue 3, pp. 700-6, (2010) (PubMed).
: "Activation of human microglia by fibrillar prion protein-related peptides is enhanced by amyloid-associated factors SAP and C1q." in: Neurobiology of disease, Vol. 19, Issue 1-2, pp. 273-82, (2005) (PubMed).
: "Use of genetically altered mice to study the role of serum amyloid P component in amyloid deposition." in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, Vol. 10 Suppl 1, pp. 17-20, (2003) (PubMed).
: "Serum amyloid P component scintigraphy for diagnosis and monitoring amyloidosis." in: Current opinion in nephrology and hypertension, Vol. 11, Issue 6, pp. 649-55, (2002) (PubMed).
Synonyms and alternative names related to APCS
amyloid P component, serum (APCS), amyloid P component, serum (Apcs), serum amyloid P-component (Apcs), amyloid P component, serum protein L homeolog (apcs.L), APCS, apcs, FP, PTX2, ptx2, SAP, Sap, sap, SAP(FP)Protein level used designations for APCS
- 9.5S alpha-1-glycoprotein
- pentaxin-related
- serum amyloid P-component
- serum amyloid P component
- amyloid P component, serum
- SAP
- pentraxin
- C-reactive protein
- amyloid P component serum
- APCS amyloid P-component serum protein
- Serum amyloid P-component
- LOW QUALITY PROTEIN: serum amyloid P-component
- Female protein
- amyloid P component, serum protein L homeolog
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