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APC1 Products

(Anaphase Promoting Complex Subunit 1 (ANAPC1))

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This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].

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Featured APC1 Categories

APC1 Antibodies

High quality antibodies with extensive validation data.

Recommended APC1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, WB, ICC, FACS, Neut
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Cat. No. ABIN5611230
Quantity 100 μL
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Reactivity Human
Application ELISA, IHC
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  • (2)
Cat. No. ABIN7144071
Quantity 100 μL
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Reactivity Human, Mouse
Application IHC, WB, IF, IC
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Cat. No. ABIN7303424
Quantity 100 μL
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Recommended APC1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
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Reactivity Human
Source Wheat germ
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Cat. No. ABIN1345024
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our APC1 products

Spurlock, Tossberg, Olsen, Aune: "Cutting Edge: Chronic NF-κB Activation in CD4+ T Cells in Rheumatoid Arthritis Is Genetically Determined by HLA Risk Alleles." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 791-5, (2015) (PubMed).

Schiffman, Rodriguez, Chen, Wacholder, Herrero, Hildesheim, Desalle, Befano, Yu, Safaeian, Sherman, Morales, Guillen, Alfaro, Hutchinson, Solomon, Castle, Burk: "A population-based prospective study of carcinogenic human papillomavirus variant lineages, viral persistence, and cervical neoplasia." in: Cancer research, Vol. 70, Issue 8, pp. 3159-69, (2010) (PubMed).

Davoli, Denchi, de Lange: "Persistent telomere damage induces bypass of mitosis and tetraploidy." in: Cell, Vol. 141, Issue 1, pp. 81-93, (2010) (PubMed).

Kraft, Herzog, Gieffers, Mechtler, Hagting, Pines, Peters: "Mitotic regulation of the human anaphase-promoting complex by phosphorylation." in: The EMBO journal, Vol. 22, Issue 24, pp. 6598-609, (2003) (PubMed).

Jörgensen, Gräslund, Betz, Ståhl, Larsson, Höög: "Characterisation of the human APC1, the largest subunit of the anaphase-promoting complex." in: Gene, Vol. 262, Issue 1-2, pp. 51-9, (2001) (PubMed).

Synonyms and alternative names related to APC1

anaphase promoting complex subunit 1 (ANAPC1), anaphase promoting complex subunit 1 (Anapc1), anaphase promoting complex subunit 1 (CC1G_09696), anaphase promoting complex subunit 1 (anapc1), E3 ubiquitin ligase (EMB2771), 2610021O03Rik, AI047775, AI853536, APC1, Apc1, AW547281, DDBDRAFT_0186456, DDBDRAFT_0234263, DDB_0186456, DDB_0234263, EMBRYO DEFECTIVE 2771, MCPR, Mcpr, MOP10.10, MOP10_10, TSG24, tsg24

Protein level used designations for APC1

  • anaphase-promoting complex 1 (meiotic checkpoint regulator)
  • anaphase-promoting complex subunit 1
  • cyclosome subunit 1
  • mitotic checkpoint regulator
  • testis-specific gene 24 protein
  • anaphase promoting complex subunit 1
  • meiotic check point regulator
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