APBA1 Products
(Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))
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The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008].
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APBA1 Antibodies
High quality antibodies with extensive validation data.
Recommended APBA1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse, Rat
Application
WB, IHC, ICC
Validations
- (1)
- (3)
Cat. No.
ABIN1742315
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IHC (p)
Validations
- (2)
Cat. No.
ABIN6736687
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC
Validations
- (2)
Cat. No.
ABIN926979
Quantity
100 μL
Datasheet
Datasheet
Recommended APBA1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3088830
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3131021
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our APBA1 products
: "Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses." in: Neuron, Vol. 78, Issue 2, pp. 285-97, (2013) (PubMed).: "Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity." in: Journal of molecular endocrinology, Vol. 38, Issue 1-2, pp. 3-17, (2007) (PubMed).
: "Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease." in: Neuroscience, Vol. 138, Issue 2, pp. 511-22, (2006) (PubMed).
: "Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14500-5, (2002) (PubMed).
: "Mints as adaptors. Direct binding to neurexins and recruitment of munc18." in: The Journal of biological chemistry, Vol. 275, Issue 51, pp. 39803-6, (2001) (PubMed).
: "Control of fusion pore dynamics during exocytosis by Munc18." in: Science (New York, N.Y.), Vol. 291, Issue 5505, pp. 875-8, (2001) (PubMed).
: "Mints, Munc18-interacting proteins in synaptic vesicle exocytosis." in: The Journal of biological chemistry, Vol. 272, Issue 50, pp. 31459-64, (1998) (PubMed).
Synonyms and alternative names related to APBA1
amyloid beta precursor protein binding family A member 1 (APBA1), amyloid beta (A4) precursor protein-binding, family A, member 1b (apba1b), ketopantoate reductase (apbA1), 2-dehydropantoate 2-reductase (apbA1), 2-dehydropantoate 2-reductase (apba1), amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) (apba1), amyloid beta (A4) precursor protein-binding, family A, member 1 (apba1), amyloid beta (A4) precursor protein binding, family A, member 1 (Apba1), amyloid beta precursor protein binding family A member 1 (Apba1), 6430513E09Rik, APBA1, D9S411E, Lin-10, LIN10, Mint, Mint1, MINT1, Urop11, X11, X11A, X11alpha, X11ALPHAProtein level used designations for APBA1
- amyloid beta (A4) precursor protein-binding, family A, member 1
- amyloid beta A4 precursor protein-binding, family A, member 1
- amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
- ketopantoate reductase
- 2-dehydropantoate 2-reductase
- Amyloid beta A4 precursor protein-binding family A member 1
- amyloid beta A4 precursor protein-binding family A member 1-like
- UROP11-110
- adapter protein X11alpha
- amyloid beta A4 precursor protein-binding family A member 1
- mint-1
- neuron-specific X11 protein
- neuronal Munc18-1-interacting protein 1
- amyloid beta (A4) precursor protein-binding family A APBA1: amyloid beta (A4) precursor protein-binding family A member 1 (X11)
- amyloid beta (A4) precursor protein-binding, family A, APBA1: amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
- adaptor protein X11alpha
- neuronal munc18-1-interacting protein 1
- phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
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