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AP5Z1 Products

(Adaptor-Related Protein Complex 5, zeta 1 Subunit (AP5Z1))
This gene was identified by genome-wide screen for genes involved in homologous recombination DNA double-strand break repair (HR-DSBR). The encoded protein was found in a complex with other proteins that have a role in HR-DSBR. Knockdown of this gene reduced homologous recombination, and mutations in this gene were found in patients with spastic paraplegia. It was concluded that this gene likely encodes a helicase (PMID:20613862). [provided by RefSeq, Jan 2011].

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Featured AP5Z1 Categories

AP5Z1 Antibodies

High quality antibodies with extensive validation data.

AP5Z1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AP5Z1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application IHC (p)
Validations
  • (1)
Cat. No. ABIN651429
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC
Validations
Cat. No. ABIN1385208
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN1393159
Quantity 100 μL
Datasheet Datasheet

Recommended AP5Z1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345272
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3089137
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3121975
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our AP5Z1 products

Hirst, Edgar, Esteves, Darios, Madeo, Chang, Roda, Dürr, Anheim, Gellera, Li, Züchner, Mariotti, Stevanin, Blackstone, Kruer, Robinson: "Loss of AP-5 results in accumulation of aberrant endolysosomes: defining a new type of lysosomal storage disease." in: Human molecular genetics, Vol. 24, Issue 17, pp. 4984-96, (2015) (PubMed).

Synonyms and alternative names related to AP5Z1

adaptor related protein complex 5 zeta 1 subunit (AP5Z1), adaptor-related protein complex 5, zeta 1 subunit (Ap5z1), C330006K01Rik, KIAA0415, SPG48, zeta

Protein level used designations for AP5Z1

  • AP-5 complex subunit zeta-1
  • adapter-related protein complex 5 zeta subunit
  • zeta5
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