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AOC3 Products

(Amine Oxidase, Copper Containing 3 (Vascular Adhesion Protein 1) (AOC3))

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This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].

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Featured AOC3 Categories

AOC3 Antibodies

High quality antibodies with extensive validation data.

AOC3 ELISA Kits

Reliable ELISA kits for a wide range of species.

AOC3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended AOC3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (5)
Cat. No. ABIN652478
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN3015816
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7159328
Quantity 100 μg
Datasheet Datasheet

Recommended AOC3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6964785
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962867
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6953656
Quantity 96 tests
Datasheet Datasheet

Recommended AOC3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1345218
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Mammalian Cells
Validations
  • (1)
Cat. No. ABIN7538130
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1345219
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our AOC3 products

Weston, Shepherd, Claridge, Rantakari, Curbishley, Tomlinson, Hubscher, Reynolds, Aalto, Anstee, Jalkanen, Salmi, Smith, Day, Adams: "Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis." in: The Journal of clinical investigation, Vol. 125, Issue 2, pp. 501-20, (2015) (PubMed).

Hernandez-Guillamon, Solé, Delgado, García-Bonilla, Giralt, Boada, Penalba, García, Flores, Ribó, Alvarez-Sabin, Ortega-Aznar, Unzeta, Montaner: "VAP-1/SSAO plasma activity and brain expression in human hemorrhagic stroke." in: Cerebrovascular diseases (Basel, Switzerland), Vol. 33, Issue 1, pp. 55-63, (2012) (PubMed).

Ma, Manaenko, Khatibi, Chen, Zhang, Tang: "Vascular adhesion protein-1 inhibition provides antiinflammatory protection after an intracerebral hemorrhagic stroke in mice." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 31, Issue 3, pp. 881-93, (2011) (PubMed).

Autio, Ujula, Luoto, Salomäki, Jalkanen, Roivainen: "PET imaging of inflammation and adenocarcinoma xenografts using vascular adhesion protein 1 targeting peptide 68Ga-DOTAVAP-P1: comparison with 18F-FDG." in: European journal of nuclear medicine and molecular imaging, Vol. 37, Issue 10, pp. 1918-25, (2010) (PubMed).

Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: "From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 6, pp. 1072-81, (2006) (PubMed).

Forster-Horváth, Döme, Paku, Ladányi, Somlai, Jalkanen, Tímár: "Loss of vascular adhesion protein-1 expression in intratumoral microvessels of human skin melanoma." in: Melanoma research, Vol. 14, Issue 2, pp. 135-40, (2004) (PubMed).

Martelius, Salaspuro, Salmi, Krogerus, Höckerstedt, Jalkanen, Lautenschlager: "Blockade of vascular adhesion protein-1 inhibits lymphocyte infiltration in rat liver allograft rejection." in: The American journal of pathology, Vol. 165, Issue 6, pp. 1993-2001, (2004) (PubMed).

Synonyms and alternative names related to AOC3

amine oxidase, copper containing 3 (AOC3), amine oxidase, copper containing 3 L homeolog (aoc3.L), amine oxidase, copper containing 3 (Aoc3), aoc2, BOLAO, HPAO, SSAO, VAP-1, VAP1

Protein level used designations for AOC3

  • amine oxidase, copper containing 3 (vascular adhesion protein 1)
  • copper amine oxidase
  • membrane primary amine oxidase
  • placenta copper monamine oxidase
  • semicarbazide-sensitive amine oxidase
  • amine oxidase, copper containing 2
  • amine oxidase, copper containing 2 (retina-specific)
  • VAP-1
  • vascular adhesion protein 1
  • VP97
  • copper containing amine oxidase 3
  • primary amine oxidase, lung isozyme
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