GLB1 antibody

Catalog No. ABIN99522

Product Details anti-GLB1 Antibody

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Reactivity: E. coli

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLB1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Dot Blot (DB)

Characteristics: Concentration Definition: by Refractometry

Immunogen: Beta Galactosidase (E.coli)
Immunogentype:Native

Application Details

Application Notes: Beta-Gal Antibody is suitable for immunoblotting (western or dot blot), ELISA, immunoprecipitation and most immunological methods requiring high titer and specificity.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Restore with deionized water (or equivalent)

Concentration: 80 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

References for anti-GLB1 antibody (ABIN99522)

Cabrera, Charron, Leib: "Neuronal Subtype Determines Herpes Simplex Virus 1 Latency-Associated-Transcript Promoter Activity during Latency." in: Journal of virology, Vol. 92, Issue 13, (2018) (PubMed).

Volckaert, Yuan, Chao, Bell, Sitaula, Szimmtenings, El Agha, Chanda, Majka, Bellusci, Thannickal, Fässler, De Langhe: "Fgf10-Hippo Epithelial-Mesenchymal Crosstalk Maintains and Recruits Lung Basal Stem Cells." in: Developmental cell, Vol. 43, Issue 1, pp. 48-59.e5, (2017) (PubMed).

Katzenell, Leib: "Herpes simplex virus and interferon signaling induce novel autophagic clusters in sensory neurons." in: Journal of virology, (2016) (PubMed).

Shearer, Fragoso, Clagett-Dame, McCaffery: "Astrocytes as a regulated source of retinoic acid for the brain." in: Glia, (2012) (PubMed).

Perry, He, Sugimura, Grindley, Haug, Ding, Li: "Cooperation between both Wnt/{beta}-catenin and PTEN/PI3K/Akt signaling promotes primitive hematopoietic stem cell self-renewal and expansion." in: Genes & development, Vol. 25, Issue 18, pp. 1928-42, (2011) (PubMed).

Target Details for GLB1

Target: GLB1 (Galactosidase, beta 1 (GLB1))

Alternative Name: Beta Galactosidase (GLB1 Products)

Background: Anti Beta Galactosidase Antibody recognizes the enzyme beta galactosidase, or β-galactosidase, that is a component of assays used frequently in genetics, molecular biology (see X-gal) for a blue white screen, and other life sciences. IPTG induces production of β-galactosidase by binding and inhibiting the lac repressor. Since it is highly expressed and accumulated in lysosomes in senescent cells, it is used as a senescence biomarker both in vivo and in vitro in qualitative and quantitative assays, despite its limitations. Anti-beta Galactosidase Antibody is ideal for investigators involved in enzyme research.
Synonyms: beta-Galactosidase, beta-galactosidase, beta-gal

Pathways: Glycosaminoglycan Metabolic Process