KSHV ORF8 antibody

Catalog No. ABIN969576

Product Details

Target: KSHV ORF8

Reactivity: Human

Host: Mouse

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB)

Immunogen: Synthetic peptide, corresponding to amino acids sequence of KSHV ORF8.

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit anti-serum.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References

Wang, Akula, Sharma-Walia, Zeng, Chandran: "Human herpesvirus 8 envelope glycoprotein B mediates cell adhesion via its RGD sequence." in: Journal of virology, Vol. 77, Issue 5, pp. 3131-47, (2003) (PubMed).

Target Details

Target: KSHV ORF8

Target Type: Viral Protein

Background:

Description: Kaposi's sarcoma-associated herpesvirus (KSHV) belongs to the gamma-(2)-herpesvirus subfamily and has been closely linked to the Kaposi's sarcoma, primary effusion lymphoma (PEL) and multicentric Castleman's disease. The genome of KSHV is 165-170 kb and contains at least 88 open reading frames. KSHV ORF8 is a virion envelope-associated protein. Akula et al (2003) report it acts as a Glycoprotein B mediated signaling during virus entry. This Glycoprotein possesses the Arg-Gly-Asp (RGD) motif and utilizes alpha3beta1 integrin as one of the receptors for its entry into the target cells.

Aliases: ORF8

Gene ID: 4961501

HGNC: 4961501