YAP1 antibody
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- Target See all YAP1 Antibodies
- YAP1 (Yes-Associated Protein 1 (YAP1))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This YAP1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Purpose
- YAP1 Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human YAP1 expressed in E. Coli.
- Clone
- 1A12
- Isotype
- IgG1
- Top Product
- Discover our top product YAP1 Primary Antibody
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." in: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).
: "YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway." in: Nature cell biology, Vol. 11, Issue 12, pp. 1444-50, (2009) (PubMed).
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YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation." in: Genes & development, Vol. 23, Issue 23, pp. 2729-41, (2009) (PubMed).
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- Target
- YAP1 (Yes-Associated Protein 1 (YAP1))
- Alternative Name
- YAP1 (YAP1 Products)
- Background
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Description: This gene encodes the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes proto-oncogene product. This protein contains a WW domain that is found in various structural, regulatory and signaling molecules in yeast, nematode, and mammals, and may be involved in protein-protein interaction.
Aliases: YAP, YKI, YAP2, YAP65
- Gene ID
- 10413
- HGNC
- 10413
- UniProt
- P46937
- Pathways
- MAPK Signaling, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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