T Antigen (AA 218-352) antibody

Catalog No. ABIN969569

Product Details

Target: T Antigen

Binding Specificity: AA 218-352

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Purification: Purified

Immunogen: Purified recombinant fragment of human T (AA 218-352) expressed in E. Coli.

Clone: 6C12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C, -20°C for long term storage

References

Shen, Li, Yang, Lu, Zou, Wang, Deng: "Classic chordoma coexisting with benign notochordal cell rest demonstrating different immunohistological expression patterns of brachyury and galectin-3." in: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, Vol. 18, Issue 1, pp. 96-9, (2010) (PubMed).

Tirabosco, Mangham, Rosenberg, Vujovic, Bousdras, Pizzolitto, De Maglio, den Bakker, Di Francesco, Kalil, Athanasou, ODonnell, McCarthy, Flanagan: "Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue." in: The American journal of surgical pathology, Vol. 32, Issue 4, pp. 572-80, (2008) (PubMed).

Target Details

Target: T Antigen

Background: The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.

Molecular Weight: 47.4 kDa

Gene ID: 6862

HGNC: 6862