RPA1 antibody

Catalog No. ABIN969564

Product Details anti-RPA1 Antibody

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RPA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: RPA1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human RPA1 expressed in E. Coli.

Clone: 4C4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RPA1 antibody (ABIN969564)

Sowd, Wang, Pretto, Chazin, Opresko: "Replication protein A stimulates the Werner syndrome protein branch migration activity." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34682-91, (2009) (PubMed).

Target Details for RPA1

Target: RPA1 (Replication Protein A1, 70kDa (RPA1))

Alternative Name: RPA1 (RPA1 Products)

Background:

Description: "This gene Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing"

Aliases: HSSB, RF-A, RP-A, REPA1, RPA70, MST075

Molecular Weight: 68.1kDa

Gene ID: 6117

HGNC: 6117

UniProt: P27694

Pathways: Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA