Nkx2-2 antibody

Catalog No. ABIN969550

Product Details anti-Nkx2-2 Antibody

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Nkx2-2 antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA

Purpose: NKX2.2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human NKX2.2 expressed in E. Coli.

Clone: 3E4

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Nkx2-2 antibody (ABIN969550)

Wang, Gallego-Arteche, Iezza, Yuan, Matli, Choo, Zuraek, Gogia, Lynn, German, Bergsland, Donner, Warren, Nakakura: "Homeodomain transcription factor NKX2.2 functions in immature cells to control enteroendocrine differentiation and is expressed in gastrointestinal neuroendocrine tumors." in: Endocrine-related cancer, Vol. 16, Issue 1, pp. 267-79, (2009) (PubMed).

Target Details for Nkx2-2

Target: Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))

Alternative Name: NKX2.2 (Nkx2-2 Products)

Background:

Description: The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor.

Aliases: NKX2B,NKX2-2

Molecular Weight: 30.1kDa

Gene ID: 4821

HGNC: 4821

UniProt: O95096

Pathways: Dopaminergic Neurogenesis