MAP2 antibody (AA 24-123)

Catalog No. ABIN969536

Product Details anti-MAP2 Antibody

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Binding Specificity: AA 24-123

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MAP2 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: MAP2 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human MAP2 (AA: 24-123) expressed in E. Coli.

Clone: 5B7

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MAP2 antibody (ABIN969536)

Jan, Adolfsson, Allaman, Buccarello, Magistretti, Pfeifer, Muhs, Lashuel: "Abeta42 neurotoxicity is mediated by ongoing nucleated polymerization process rather than by discrete Abeta42 species." in: The Journal of biological chemistry, Vol. 286, Issue 10, pp. 8585-96, (2011) (PubMed).

Gambichler, Rotterdam, Radkowski, Altmeyer, Kreuter: "Differential expression of microtubule-associated protein 2 in melanocytic skin lesions." in: American journal of clinical pathology, Vol. 131, Issue 5, pp. 710-4, (2009) (PubMed).

Target Details for MAP2

Target: MAP2 (Microtubule-Associated Protein 2 (MAP2))

Alternative Name: MAP2 (MAP2 Products)

Synonyms: MAP2A antibody, MAP2B antibody, MAP2C antibody, MAP2R antibody, Mtap2 antibody, MAP-2 antibody, Mtap-2 antibody, xmap2 antibody, MGC53131 antibody, a730034c02 antibody, zgc:103474 antibody, zgc:113974 antibody, microtubule associated protein 2 antibody, microtubule-associated protein 2 antibody, microtubule associated protein 2 S homeolog antibody, MAP2 antibody, Map2 antibody, map2.S antibody, map2 antibody

Background:

Description: This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.

Aliases: MAP2A, MAP2B, MAP2C

Molecular Weight: 199kDa

Gene ID: 4133

HGNC: 4133

UniProt: P11137