ITGA4 antibody

Catalog No. ABIN969530

Product Details anti-ITGA4 Antibody

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of human ITGA4 expressed in E. coli.

Clone: 5C4

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-ITGA4 antibody (ABIN969530)

Correia, Coutinho, Almeida, Lontro, Lobo, Miguel, Martins, Gallagher, Conroy, Gill, Oliveira, Vicente: "Association of the alpha4 integrin subunit gene (ITGA4) with autism." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 150B, Issue 8, pp. 1147-51, (2009) (PubMed).

Nückel, Switala, Collins, Sellmann, Grosse-Wilde, Dührsen, Rebmann: "High CD49d protein and mRNA expression predicts poor outcome in chronic lymphocytic leukemia." in: Clinical immunology (Orlando, Fla.), Vol. 131, Issue 3, pp. 472-80, (2009) (PubMed).

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: ITGA4 (ITGA4 Products)

Synonyms: CD49D antibody, IA4 antibody, LOC100219853 antibody, integrin subunit alpha 4 antibody, integrin alpha 4 antibody, integrin subunit alpha 4 S homeolog antibody, ITGA4 antibody, Itga4 antibody, itga4.S antibody

Background:

Description: The product of this gene belongs to the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an alpha 4 chain. Unlike other integrin alpha chains, alpha 4 neither contains an I-domain, nor undergoes disulfide-linked cleavage. Alpha 4 chain associates with either beta 1 chain or beta 7 chain.

Aliases: IA4, CD49D

Molecular Weight: 115 kDa

Gene ID: 3676

HGNC: 3676

Pathways: Integrin Complex