HSF4 antibody

Catalog No. ABIN969527

Product Details anti-HSF4 Antibody

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSF4 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Purpose: HSF4 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human HSF4 expressed in E. Coli.

Clone: 2E7

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-HSF4 antibody (ABIN969527)

Ma, Zhang, Li, Xi, Hu: "[Construction of eukaryotic plasmid expression Hsf4b and phosphorylation of Hsf4b by MAP kinase P38]." in: Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, Vol. 26, Issue 4, pp. 325-8, (2010) (PubMed).

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

Target Details for HSF4

Target: HSF4 (Heat Shock Transcription Factor 4 (HSF4))

Alternative Name: HSF4 (HSF4 Products)

Synonyms: CTM antibody, CTRCT5 antibody, HSF 4 antibody, HSTF 4 antibody, HSTF4 antibody, ldis1 antibody, mHSF4 antibody, zgc:113344 antibody, heat shock transcription factor 4 antibody, HSF4 antibody, Hsf4 antibody, hsf4 antibody

Background:

Description: Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

Aliases: CTM

Molecular Weight: 53kDa

Gene ID: 3299

HGNC: 3299

UniProt: Q9ULV5

Pathways: MAPK Signaling