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GRIA2 antibody (AA 652-807)

GRIA2 Reactivity: Human WB, ELISA, FACS Host: Mouse Monoclonal 7G6 unconjugated
Catalog No. ABIN969524
  • Target See all GRIA2 Antibodies
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    Binding Specificity
    • 29
    • 16
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 652-807
    Reactivity
    • 93
    • 73
    • 68
    • 13
    • 11
    • 11
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 92
    • 9
    Mouse
    Clonality
    • 83
    • 18
    Monoclonal
    Conjugate
    • 49
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This GRIA2 antibody is un-conjugated
    Application
    • 78
    • 27
    • 27
    • 24
    • 23
    • 16
    • 15
    • 8
    • 6
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Purpose
    GRIA2 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human GRIA2 (AA: 652-807) expressed in E. Coli.
    Clone
    7G6
    Isotype
    IgG1
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Yu, Wu, Fu, Cheng, Yang, Chen, Long, Chen, Wang: "Aging-related alterations in the expression and distribution of GluR2 and PICK1 in the rat hippocampus." in: Neuroscience letters, Vol. 497, Issue 1, pp. 42-5, (2011) (PubMed).

    Shen, Jin: "[GluR2 expression in the developing rat inferior colliculus and the relationship with development of synapse]." in: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, Vol. 24, Issue 4, pp. 173-6, (2010) (PubMed).

  • Target
    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))
    Alternative Name
    GRIA2 (GRIA2 Products)
    Synonyms
    GLUR2 antibody, GLURB antibody, GluA2 antibody, GluR-K2 antibody, HBGR2 antibody, GluR-2 antibody, GluR-B antibody, Glur-2 antibody, Glur2 antibody, GluR2 antibody, gluR-B antibody, glur2a antibody, gria2.1 antibody, zfGRIA2[a] antibody, glur2 antibody, glutamate ionotropic receptor AMPA type subunit 2 antibody, glutamate receptor, ionotropic, AMPA 2 antibody, glutamate receptor, ionotropic, AMPA2 (alpha 2) antibody, glutamate receptor, ionotropic, AMPA 2a antibody, glutamate receptor, ionotropic, AMPA 2 S homeolog antibody, GRIA2 antibody, Gria2 antibody, gria2a antibody, gria2.S antibody
    Background

    Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene.

    Aliases: GluA2, GluR2, gluR-B, GluR-K2

    Molecular Weight
    98.8kDa
    Gene ID
    2891
    HGNC
    29627
    UniProt
    P42262
    Pathways
    PI3K-Akt Signaling
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