FOXO1 antibody

Catalog No. ABIN969521

Product Details anti-FOXO1 Antibody

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOXO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Purpose: FOXO1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human FOXO1 expressed in E. Coli.

Clone: 3B6

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-FOXO1 antibody (ABIN969521)

Lau, Koty, Nalbantoglu: "Differential response of glioma cells to FOXO1-directed therapy." in: Cancer research, Vol. 69, Issue 13, pp. 5433-40, (2009) (PubMed).

Srivastava, Yasruel, Nalbantoglu: "Impaired medulloblastoma cell survival following activation of the FOXO1 transcription factor." in: International journal of oncology, Vol. 35, Issue 5, pp. 1045-51, (2009) (PubMed).

Target Details for FOXO1

Target: FOXO1 (Forkhead Box O1 (FOXO1))

Alternative Name: FOXO1 (FOXO1 Products)

Synonyms: FKH1 antibody, FKHR antibody, FOXO1A antibody, FoxO1a.1 antibody, foxo1 antibody, zgc:153388 antibody, Fkhr antibody, Foxo1a antibody, AI876417 antibody, Afxh antibody, Fkhr1 antibody, fkh1 antibody, fkhr antibody, foxo1a antibody, xFoxO1 antibody, FoxO1A antibody, foxo1a.2 antibody, forkhead box O1 antibody, forkhead box O1 a antibody, forkhead box O1 L homeolog antibody, forkhead box O1 b antibody, FOXO1 antibody, foxo1a antibody, Foxo1 antibody, foxo1 antibody, foxo1.L antibody, foxo1b antibody

Background:

Description: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined, however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.

Aliases: FKH1, FKHR, FOXO1A

Molecular Weight: 69.7kDa

Gene ID: 2308

HGNC: 2308

UniProt: Q12778

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Carbohydrate Metabolic Process, CXCR4-mediated Signaling Events, BCR Signaling