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EIF4B antibody

EIF4B Reactivity: Human WB, ELISA, IHC, FACS, ICC Host: Mouse Monoclonal 1F5 unconjugated
Catalog No. ABIN969517
  • Target See all EIF4B Antibodies
    EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
    Reactivity
    • 93
    • 46
    • 32
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 81
    • 10
    • 2
    Mouse
    Clonality
    • 81
    • 12
    Monoclonal
    Conjugate
    • 52
    • 6
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EIF4B antibody is un-conjugated
    Application
    • 78
    • 38
    • 31
    • 17
    • 17
    • 15
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purpose
    EIF4B Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human EIF4B expressed in E. Coli.
    Clone
    1F5
    Isotype
    IgG2b
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Mokas, Mills, Garreau, Fournier, Robert, Arya, Kaufman, Pelletier, Mazroui: "Uncoupling stress granule assembly and translation initiation inhibition." in: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, (2009) (PubMed).

    Shahbazian, Roux, Mieulet, Cohen, Raught, Taunton, Hershey, Blenis, Pende, Sonenberg: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." in: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, (2006) (PubMed).

  • Target
    EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
    Alternative Name
    EIF4B (EIF4B Products)
    Background

    Description: The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F

    Aliases: EIF-4B, PRO1843

    Molecular Weight
    80kDa
    Gene ID
    1975
    HGNC
    1975
    UniProt
    P23588
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