EIF4B antibody
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- Target See all EIF4B Antibodies
- EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This EIF4B antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purpose
- EIF4B Antibody
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human EIF4B expressed in E. Coli.
- Clone
- 1F5
- Isotype
- IgG2b
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Uncoupling stress granule assembly and translation initiation inhibition." in: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, (2009) (PubMed).
: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." in: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, (2006) (PubMed).
: "
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Uncoupling stress granule assembly and translation initiation inhibition." in: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, (2009) (PubMed).
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- Target
- EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))
- Alternative Name
- EIF4B (EIF4B Products)
- Background
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Description: The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F
Aliases: EIF-4B, PRO1843
- Molecular Weight
- 80kDa
- Gene ID
- 1975
- HGNC
- 1975
- UniProt
- P23588
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