COTL1 antibody
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- Target See all COTL1 Antibodies
- COTL1 (Coactosin-Like Protein)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This COTL1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant fragment of human COTL1 expressed in E. coli.
- Clone
- 5C8
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders." in: Experimental & molecular medicine, Vol. 41, Issue 5, pp. 354-61, (2009) (PubMed).
: "
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Polymorphisms of COTL1 gene identified by proteomic approach and their association with autoimmune disorders." in: Experimental & molecular medicine, Vol. 41, Issue 5, pp. 354-61, (2009) (PubMed).
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- Target
- COTL1 (Coactosin-Like Protein)
- Alternative Name
- COTL1 (COTL1 Products)
- Synonyms
- CLP antibody, 1810074P22Rik antibody, 2010004C08Rik antibody, Clp antibody, coactosin like F-actin binding protein 1 antibody, coactosin-like 1 (Dictyostelium) antibody, coactosin-like F-actin binding protein 1 antibody, COTL1 antibody, Cotl1 antibody
- Background
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Description: This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
Aliases: CLP
- Molecular Weight
- 16 kDa
- Gene ID
- 23406
- HGNC
- 23406
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