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Cytokeratin 5 antibody

KRT5 Reactivity: Human WB, IHC, ELISA, FACS, ICC Host: Mouse Monoclonal 2C2 unconjugated
Catalog No. ABIN969508
  • Target See all Cytokeratin 5 (KRT5) Antibodies
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    Reactivity
    • 127
    • 78
    • 53
    • 10
    • 10
    • 10
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 92
    • 42
    • 2
    Mouse
    Clonality
    • 83
    • 53
    Monoclonal
    Conjugate
    • 59
    • 13
    • 10
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    This Cytokeratin 5 antibody is un-conjugated
    Application
    • 86
    • 48
    • 45
    • 28
    • 24
    • 19
    • 14
    • 14
    • 13
    • 9
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Purpose
    CK5 Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CK5 expressed in E. Coli.
    Clone
    2C2
    Isotype
    IgG1
    Top Product
    Discover our top product KRT5 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Grin, OMalley, Mulligan: "Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy." in: The American journal of surgical pathology, Vol. 33, Issue 11, pp. 1615-23, (2009) (PubMed).

    Sugiyama-Fukamatsu, Suzuki, Nakanishi, Iwatsuki: "Epidermolysis bullosa nevus arising in a patient with Dowling-Meara type epidermolysis bullosa simplex with a novel K5 mutation." in: The Journal of dermatology, Vol. 36, Issue 8, pp. 447-52, (2009) (PubMed).

  • Target
    Cytokeratin 5 (KRT5) (Keratin 5 (KRT5))
    Alternative Name
    CK5 (KRT5 Products)
    Background

    Description: The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

    Aliases: KRT5, K5, DDD, EBS2, KRT5A

    Molecular Weight
    62.3kDa
    Gene ID
    3852
    HGNC
    3852
    UniProt
    P13647
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