ARHGDIA antibody (AA 1-204)

Catalog No. ABIN969501

Product Details anti-ARHGDIA Antibody

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Binding Specificity: AA 1-204

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ARHGDIA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: ARHGDIA Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ARHGDIA (AA: FULL(1-204)) expressed in E. Coli.

Clone: 2G3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-ARHGDIA antibody (ABIN969501)

Bartos, Ramakrishnan, Braga-Lagache, Hänzi, Durussel, Prakash Sridharan, Zhu, Sheehan, Hynes, Bonny, Moor: "Renal FGF23 signaling depends on redox protein Memo1 and promotes orthovanadate-sensitive protein phosphotyrosyl phosphatase activity." in: Journal of cell communication and signaling, (2022) (PubMed).

Boulter, Garcia-Mata, Guilluy, Dubash, Rossi, Brennwald, Burridge: "Regulation of Rho GTPase crosstalk, degradation and activity by RhoGDI1." in: Nature cell biology, Vol. 12, Issue 5, pp. 477-83, (2010) (PubMed).

Ronneburg, Span, Kantelhardt, Dittmer, Schunke, Holzhausen, Sweep, Dittmer: "Rho GDP dissociation inhibitor alpha expression correlates with the outcome of CMF treatment in invasive ductal breast cancer." in: International journal of oncology, Vol. 36, Issue 2, pp. 379-86, (2009) (PubMed).

Target Details for ARHGDIA

Target: ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))

Alternative Name: ARHGDIA (ARHGDIA Products)

Background:

Description: Aplysia Ras-related homologs (ARHs), also called Rho genes, belong to the RAS gene superfamily encoding small guanine nucleotide exchange (GTP/GDP) factors. The ARH proteins may be kept in the inactive, GDP-bound state by interaction with GDP dissociation inhibitors, such as ARHGDIA

Aliases: GDIA1,RHOGDI,RHOGDI-1

Molecular Weight: 26kDa

Gene ID: 396

HGNC: 396

UniProt: P52565

Pathways: Neurotrophin Signaling Pathway