S100A6 antibody

Catalog No. ABIN969470

Product Details anti-S100A6 Antibody

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A6 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Purpose: S100A6 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of calcyclin expressed in E. Coli.

Clone: 7D11

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-S100A6 antibody (ABIN969470)

Bean, Salamon, Raffaello, Campanaro, Pallavicini, Lanfranchi: "The Ankrd2, Cdkn1c and calcyclin genes are under the control of MyoD during myogenic differentiation." in: Journal of molecular biology, Vol. 349, Issue 2, pp. 349-66, (2005) (PubMed).

Hwang, Lee, Kim, Li, Jin, Rhee, Kim, Lim: "Calcyclin, a Ca2+ ion-binding protein, contributes to the anabolic effects of simvastatin on bone." in: The Journal of biological chemistry, Vol. 279, Issue 20, pp. 21239-47, (2004) (PubMed).

Target Details for S100A6

Target: S100A6 (S100 Calcium Binding Protein A6 (S100A6))

Alternative Name: S100A6 (S100A6 Products)

Synonyms: S100A6 antibody, 2A9 antibody, 5B10 antibody, CABP antibody, CACY antibody, PRA antibody, CALCYCLIN antibody, Cacy antibody, S100 calcium binding protein A6 antibody, uncharacterized LOC618256 antibody, S100 calcium binding protein A6 (calcyclin) antibody, S100A6 antibody, S100a6 antibody, LOC618256 antibody

Background:

Description: Calcyclin encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.

Aliases: S100A6, 2A9, PRA, 5B10, CABP, CACY

Gene ID: 6277

HGNC: 27101

UniProt: P06703

Pathways: S100 Proteins