WNT5A antibody
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- Target See all WNT5A Antibodies
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This WNT5A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Purification
- purified
- Immunogen
- Purified recombinant fragment of WNT5A expressed in E. coli.
- Clone
- 3D10
- Isotype
- IgG1
- Top Product
- Discover our top product WNT5A Primary Antibody
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 10, pp. 3919-24, (2009) (PubMed).
: "Prostate cancer induces bone metastasis through Wnt-induced bone morphogenetic protein-dependent and independent mechanisms." in: Cancer research, Vol. 68, Issue 14, pp. 5785-94, (2008) (PubMed).
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Wnt-5a signaling restores tamoxifen sensitivity in estrogen receptor-negative breast cancer cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 10, pp. 3919-24, (2009) (PubMed).
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- Target
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
- Alternative Name
- WNT5A (WNT5A Products)
- Synonyms
- hWNT5A antibody, wnt-5A antibody, wnt5a-B antibody, WNT5A antibody, 8030457G12Rik antibody, Wnt-5a antibody, Wnt family member 5A antibody, Wnt family member 5A S homeolog antibody, wingless-type MMTV integration site family, member 5a antibody, wingless-type MMTV integration site family, member 5A antibody, wingless-related MMTV integration site 5A antibody, Wnt signaling ligand antibody, WNT5A antibody, Wnt5a antibody, wnt5a.S antibody, wnt5a antibody, LOC578814 antibody, wnt5 antibody
- Background
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Description: WNT5A: wingless-type MMTV integration site family, member 5A. Entrez Protein: NP_003383. The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 % , 98 % and 87 % amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.
Aliases: hWNT5A,
- Molecular Weight
- 42.3 kDa
- Gene ID
- 7474
- HGNC
- 7474
- Pathways
- WNT Signaling, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation
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