WIF1 antibody

Catalog No. ABIN969457

Product Details anti-WIF1 Antibody

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This WIF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purification: purified

Immunogen: Purified recombinant fragment of human WIF1 expressed in E. coli.

Clone: 1G5

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-WIF1 antibody (ABIN969457)

Kawakami, Hirata, Yamamura, Kikuno, Saini, Majid, Tanaka, Kawamoto, Enokida, Nakagawa, Dahiya: "Functional significance of Wnt inhibitory factor-1 gene in kidney cancer." in: Cancer research, Vol. 69, Issue 22, pp. 8603-10, (2009) (PubMed).

Veeck, Wild, Fuchs, Schüffler, Hartmann, Knüchel, Dahl: "Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer." in: BMC cancer, Vol. 9, pp. 217, (2009) (PubMed).

Target Details for WIF1

Target: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Alternative Name: WIF1 (WIF1 Products)

Synonyms: shf antibody, GB10372 antibody, wif-1 antibody, WIF1 antibody, WIF-1 antibody, AW107799 antibody, zgc:110507 antibody, protein shifted antibody, wnt inhibitory factor 1 antibody, WNT inhibitory factor 1 antibody, Wnt inhibitory factor 1 antibody, WNT inhibitory factor 1 S homeolog antibody, LOC552805 antibody, CpipJ_CPIJ003761 antibody, wif1 antibody, WIF1 antibody, Wif1 antibody, LOC100511326 antibody, wif1.S antibody

Background:

Description: The protein encoded by this gene functions to inhibit WNT proteins, which are extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation. This gene functions as a tumor suppressor gene, and has been found to be epigenetically silenced in various cancers.

Aliases: WIF-1, WIF

Molecular Weight: 42 kDa

Gene ID: 11197

HGNC: 11197

Pathways: WNT Signaling, Positive Regulation of fat Cell Differentiation