T-Box 5 antibody

Catalog No. ABIN969432

Product Details anti-T-Box 5 Antibody

Target: T-Box 5 (TBX5)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This T-Box 5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: TBX5 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of TBX5 expressed in E. Coli.

Clone: 7B11

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-T-Box 5 antibody (ABIN969432)

Collavoli, Hatcher, He, Okin, Deo, Basson: "TBX5 nuclear localization is mediated by dual cooperative intramolecular signals." in: Journal of molecular and cellular cardiology, Vol. 35, Issue 10, pp. 1191-5, (2003) (PubMed).

Target Details for T-Box 5

Target: T-Box 5 (TBX5)

Alternative Name: TBX5 (TBX5 Products)

Background:

Description: TBX5, also known as T-box 5. It is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. It is closely linked to related family member T-box 3 (ulnar mammary syndrome) on human chromosome 12. The TBX5 protein may play a role in heart development and specification of limb identity. Mutations in this gene have been associated with Holt-Oram syndrome, a developmental disorder affecting the heart and upper limbs. Several transcript variants encoding different isoforms have been described for this gene.

Aliases: HOS, TBX5

Molecular Weight: 53kDa

Gene ID: 6910

HGNC: 6910

UniProt: Q99593