SMAD4 antibody
(2 references)-
- Target See all SMAD4 Antibodies
- SMAD4 (SMAD Family Member 4 (SMAD4))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This SMAD4 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Purpose
- SMAD4 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human SMAD4 expressed in E. Coli.
- Clone
- 4G1C6
- Isotype
- IgG1
- Top Product
- Discover our top product SMAD4 Primary Antibody
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anti-SMAD Family Member 4 (SMAD4) (N-Term) antibody
SMAD4 Reactivity: Human WB, IP, CUT&RUN Host: Rabbit Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 1-552) antibodySMAD4 Reactivity: Human WB, ELISA, IF, PLA Host: Mouse Monoclonal 3E2 unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodyKO Validated SMAD4 Reactivity: Human WB, IHC, IP Host: Rabbit Monoclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 255-284) antibodySMAD4 Reactivity: Human, Mouse WB, IF Host: Rabbit Polyclonal RB14714 unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 400-428) antibodySMAD4 Reactivity: Human WB, ELISA, IHC, IF, FACS Host: Rabbit Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 27-195) antibodySMAD4 Reactivity: Human WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 400-428), (C-Term) antibodySMAD4 Reactivity: Human WB, IF, IHC (p), FACS Host: Rabbit Polyclonal RB20720 unconjugated
anti-SMAD Family Member 4 (SMAD4) (pThr277) antibodySMAD4 Reactivity: Human ELISA, IHC, IF, DB Host: Rabbit Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) (AA 9-231) antibodySMAD4 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-SMAD Family Member 4 (SMAD4) antibodySMAD4 Reactivity: Human, Mouse, Rat WB, IHC (p), IF (cc) Host: Rabbit Monoclonal 3A1 unconjugated
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- Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "MicroRNA-224 is involved in transforming growth factor-beta-mediated mouse granulosa cell proliferation and granulosa cell function by targeting Smad4." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 3, pp. 540-51, (2010) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
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: "MicroRNA-224 is involved in transforming growth factor-beta-mediated mouse granulosa cell proliferation and granulosa cell function by targeting Smad4." in: Molecular endocrinology (Baltimore, Md.), Vol. 24, Issue 3, pp. 540-51, (2010) (PubMed).
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- Target
- SMAD4 (SMAD Family Member 4 (SMAD4))
- Alternative Name
- SMAD4 (SMAD4 Products)
- Background
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Description: Common mediator of signal transduction by TGF-beta (transforming growth factor) superfamily, SMAD4 is the common SMAD (co-SMAD). Promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. May act as a tumor suppressor Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome.
Aliases: JIP, DPC4, MADH4, SMAD4
- Molecular Weight
- 65kDa
- Gene ID
- 4089
- HGNC
- 4089
- UniProt
- Q13485
- Pathways
- Cell Division Cycle, Chromatin Binding, Autophagy
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