Mammaglobin A antibody

Catalog No. ABIN969392

Product Details anti-Mammaglobin A Antibody

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Mammaglobin A antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: SCGB2A2 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human SCGB2A2 expressed in E. Coli.

Clone: 3C8

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Mammaglobin A antibody (ABIN969392)

Sasaki, Tsunoda, Hatanaka, Mori, Iwata, Yatabe: "Breast-specific expression of MGB1/mammaglobin: an examination of 480 tumors from various organs and clinicopathological analysis of MGB1-positive breast cancers." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 20, Issue 2, pp. 208-14, (2007) (PubMed).

Gargano, Agnese, Calò, Corsale, Augello, Bruno, La Paglia, Gullo, Ottini, Russo, Fulfaro, Rinaldi, Crosta, Cicero, Majorana, Palmeri, Cipolla, Agrusa, Gulotta, Morello, Di Fede, Adamo, Colucci et al.: "Detection and quantification of mammaglobin in the blood of breast cancer patients: can it be useful as a potential clinical marker? Preliminary results of a GOIM (Gruppo Oncologico dell'Italia ..." in: Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, Vol. 17 Suppl 7, pp. vii41-5, (2006) (PubMed).

Target Details for Mammaglobin A

Target: Mammaglobin A (SCGB2A2) (Secretoglobin, Family 2A, Member 2 (SCGB2A2))

Alternative Name: SCGB2A2 (SCGB2A2 Products)

Synonyms: MGB1 antibody, UGB2 antibody, secretoglobin family 2A member 2 antibody, secretoglobin, family 2A, member 2 antibody, SCGB2A2 antibody, Scgb2a2 antibody

Background:

Description: Mammaglobin is a gene that is expressed almost exclusively in the normal breast epithelium and human breast cancer. It is a member of the secretoglobin gene family and forms a heterodimer with lipophilin B. It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement.Tissue specificity: Mammary gland specific. Over-expressed in breast cancer.

Aliases: MGB1, UGB2, MGC71974, SCGB2A2

Molecular Weight: 11kDa

Gene ID: 4250

HGNC: 4250

UniProt: Q13296