RUNX1 antibody

Catalog No. ABIN969390

Product Details anti-RUNX1 Antibody

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RUNX1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: RUNX1 Antibody

Purification: Ascitic fluid

Immunogen: Synthesized peptide of human RUNX1.

Clone: 2B5

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RUNX1 antibody (ABIN969390)

Marshall, Moore, Ohki, Kitabayashi, Patterson, Ornelles: "RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." in: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).

Ichikawa, Goyama, Asai, Kawazu, Nakagawa, Takeshita, Chiba, Ogawa, Kurokawa: "AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4402-8, (2008) (PubMed).

Target Details for RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Alternative Name: RUNX1 (RUNX1 Products)

Synonyms: RUNX1 antibody, runx1 antibody, AI462102 antibody, AML1 antibody, Cbfa2 antibody, Pebp2a2 antibody, Pebpa2b antibody, AML1-EVI-1 antibody, AMLCR1 antibody, CBFA2 antibody, EVI-1 antibody, PEBP2aB antibody, runxa antibody, Runx-1 antibody, XAML antibody, Xaml1 antibody, aml antibody, aml-1 antibody, aml1 antibody, aml1-evi-1 antibody, amlcr1 antibody, cbfa2 antibody, evi-1 antibody, pebp2ab antibody, Aml1 antibody, uncharacterized LOC473981 antibody, runt-related transcription factor antibody, runt related transcription factor 1 antibody, runt-related transcription factor 1 antibody, runt related transcription factor 1 L homeolog antibody, LOC473981 antibody, runt antibody, Runx1 antibody, RUNX1 antibody, runx1 antibody, runx1.L antibody

Background:

Description: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Aliases: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, RUNX1

Molecular Weight: 55kDa

Gene ID: 861

HGNC: 861

UniProt: Q01196