Reticulon 3 antibody
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- Target See all Reticulon 3 (RTN3) Antibodies
- Reticulon 3 (RTN3)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Reticulon 3 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of RTN3 expressed in E. coli.
- Clone
- 10A8
- Isotype
- IgG2a
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- Application Notes
- ELISA: 1:10000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Selenoprotein W as molecular target of methylmercury in human neuronal cells is down-regulated by GSH depletion." in: Biochemical and biophysical research communications, Vol. 330, Issue 4, pp. 1095-102, (2005) (PubMed).
: "Identification of a new RTN3 transcript, RTN3-A1, and its distribution in adult mouse brain." in: Brain research. Molecular brain research, Vol. 138, Issue 2, pp. 236-43, (2005) (PubMed).
: "Reticulon 3 is involved in membrane trafficking between the endoplasmic reticulum and Golgi." in: Biochemical and biophysical research communications, Vol. 334, Issue 4, pp. 1198-205, (2005) (PubMed).
: "A reticular rhapsody: phylogenic evolution and nomenclature of the RTN/Nogo gene family." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 17, Issue 10, pp. 1238-47, (2003) (PubMed).
: "
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Selenoprotein W as molecular target of methylmercury in human neuronal cells is down-regulated by GSH depletion." in: Biochemical and biophysical research communications, Vol. 330, Issue 4, pp. 1095-102, (2005) (PubMed).
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- Target
- Reticulon 3 (RTN3)
- Alternative Name
- RTN3 (RTN3 Products)
- Synonyms
- ASYIP antibody, HAP antibody, NSPL2 antibody, NSPLII antibody, RTN3-A1 antibody, MGC56439 antibody, zgc:56439 antibody, zgc:77630 antibody, RTN3 antibody, hap antibody, asyip antibody, nspl2 antibody, xrtn3 antibody, nsplii antibody, rtn3-a1 antibody, RTN3w antibody, rtn3 antibody, XRTN3 antibody, rtn3-a antibody, rtn3-b antibody, reticulon 3 antibody, reticulon 3 L homeolog antibody, reticulon-3 antibody, reticulon 3 S homeolog antibody, RTN3 antibody, Rtn3 antibody, rtn3 antibody, rnt3 antibody, rtn3.L antibody, LOC107131155 antibody, rtn3.S antibody
- Background
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Description: RTN3, reticulon 3. The reticulons are a group of highly conserved genes with preferential expression in neuroendocrine tissues. RTN3 may be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. There are 5 isoforms.
Aliases: HAP, ASYIP, NSPL2, NSPLII, RTN3-A1
- Molecular Weight
- 113 kDa
- Gene ID
- 10313
- HGNC
- 10313
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