MST1R antibody (AA 210-320)

Catalog No. ABIN969384

Product Details anti-MST1R Antibody

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Binding Specificity: AA 210-320

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MST1R antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: purified

Immunogen: Purified recombinant fragment of human RON (aa210-320) expressed in E. coli.

Clone: 1B5A9

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10000, WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: 4°C, -20°C for long term storage

References for anti-MST1R antibody (ABIN969384)

Zhang, Yao, Wang: "Activation of RON differentially regulates claudin expression and localization: role of claudin-1 in RON-mediated epithelial cell motility." in: Carcinogenesis, Vol. 29, Issue 3, pp. 552-9, (2008) (PubMed).

Lee, Chen, Chow, Su, Lin, Guo: "Prognostic significance of co-expression of RON and MET receptors in node-negative breast cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 6, pp. 2222-8, (2005) (PubMed).

Mallakin, Kutcher, McDowell, Kong, Schuster, Lentsch, Aronow, Leikauf, Waltz: "Gene expression profiles of Mst1r-deficient mice during nickel-induced acute lung injury." in: American journal of respiratory cell and molecular biology, Vol. 34, Issue 1, pp. 15-27, (2005) (PubMed).

Target Details for MST1R

Target: MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))

Alternative Name: RON (MST1R Products)

Synonyms: CD136 antibody, CDw136 antibody, PTK8 antibody, RON antibody, Fv-2 antibody, Fv2 antibody, Ron antibody, STK antibody, Cdw136 antibody, Ptk8 antibody, Stk antibody, macrophage stimulating 1 receptor antibody, macrophage stimulating 1 receptor (c-met-related tyrosine kinase) antibody, MST1R antibody, Mst1r antibody

Background:

Description: RON (MST1R): macrophage stimulating 1 receptor (c-met-related tyrosine kinase). RON is a receptor tyrosine kinase that is translated as a single polypeptide and then proteolytically cleaved to yield a mature heterodimer consisting of an extracellular 35 kDa α chain disulfide-linked to a membrane-spanning 150 kDa β chain.

Aliases: PTK8, CD136, CDw136, MST1R

Molecular Weight: 152 kDa

Gene ID: 4486

HGNC: 4486

Pathways: RTK Signaling