RICTOR antibody

Catalog No. ABIN969382

Product Details anti-RICTOR Antibody

Target: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RICTOR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: RICTOR Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human RICTOR expressed in E. Coli.

Clone: 7B3

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RICTOR antibody (ABIN969382)

Yang, Inoki, Ikenoue, Guan: "Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity." in: Genes & development, Vol. 20, Issue 20, pp. 2820-32, (2006) (PubMed).

Target Details for RICTOR

Target: RICTOR (RPTOR Independent Companion of mTOR, Complex 2 (RICTOR))

Alternative Name: RICTOR (RICTOR Products)

Synonyms: PIA antibody, mAVO3 antibody, 4921505C17Rik antibody, 6030405M08Rik antibody, AVO3 antibody, AW492497 antibody, D530039E11Rik antibody, Fyb antibody, RPTOR independent companion of MTOR complex 2 antibody, RPTOR independent companion of MTOR, complex 2 antibody, RICTOR antibody, Rictor antibody

Background:

Description: Cell growth is a fundamental biological process whereby cells accumulate mass and increase in size. The mammalian TOR (mTOR) pathway regulates growth by coordinating energy and nutrient signals with growth factor-derived signals . mTOR is a large protein kinase with two different complexes. One complex contains mTOR, G

Aliases: PIA, mAVO3, KIAA1999, MGC39830, DKFZp686B11164, RICTOR

Molecular Weight: 192kDa

Gene ID: 253260

HGNC: 253260

UniProt: Q6R327

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events