RBP4 antibody

Catalog No. ABIN969380

Product Details anti-RBP4 Antibody

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RBP4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Purpose: RBP4 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human RBP expressed in E. Coli.

Clone: 4C2

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RBP4 antibody (ABIN969380)

van Hoek, Dehghan, Zillikens, Hofman, Witteman, Sijbrands: "An RBP4 promoter polymorphism increases risk of type 2 diabetes." in: Diabetologia, Vol. 51, Issue 8, pp. 1423-8, (2008) (PubMed).

Choi, Kwak, Youn, Lim, Park, Lee, Lee, Cho, Lee, Kim, Park, Jang: "High plasma retinol binding protein-4 and low plasma adiponectin concentrations are associated with severity of glucose intolerance in women with previous gestational diabetes mellitus." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 8, pp. 3142-8, (2008) (PubMed).

Target Details for RBP4

Target: RBP4 (Retinol Binding Protein 4, Plasma (RBP4))

Alternative Name: RBP4 (RBP4 Products)

Synonyms: RDCCAS antibody, RBP antibody, RNBP antibody, rbp4 antibody, MGC54038 antibody, srbp antibody, PRBP antibody, RBPA antibody, Rbp-4 antibody, fb23c12 antibody, rbp antibody, wu:fb23c12 antibody, wu:fb58d04 antibody, wu:fb72b04 antibody, zgc:86911 antibody, retinol binding protein 4 antibody, renin binding protein antibody, retinol binding protein 4 S homeolog antibody, retinol binding protein 4 A, plasma antibody, retinol binding protein 4, plasma antibody, retinol binding protein 4 L homeolog antibody, RBP4 antibody, RENBP antibody, rbp4.S antibody, rbp4 antibody, Rbp4 antibody, RBP4A antibody, rbp4.L antibody

Background:

Description: This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. (provided by RefSeq)

Aliases: RBP4

Molecular Weight: 23kDa

Gene ID: 5950

HGNC: 5950

UniProt: P02753

Pathways: Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response