RAB25 antibody

Catalog No. ABIN969377

Product Details anti-RAB25 Antibody

Target: RAB25 (RAB25, Member RAS Oncogene Family (RAB25))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This RAB25 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Purpose: Rab25 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of Rab25 expressed in E. Coli.

Clone: 3F12

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RAB25 antibody (ABIN969377)

Wang, Kumar, Navarre, Casanova, Goldenring: "Regulation of vesicle trafficking in madin-darby canine kidney cells by Rab11a and Rab25." in: The Journal of biological chemistry, Vol. 275, Issue 37, pp. 29138-46, (2000) (PubMed).

Target Details for RAB25

Target: RAB25 (RAB25, Member RAS Oncogene Family (RAB25))

Alternative Name: Rab25 (RAB25 Products)

Synonyms: MGC84182 antibody, RAB25 antibody, catx-8 antibody, MGC79587 antibody, rab25 antibody, si:dkeyp-84f11.7 antibody, zgc:101648 antibody, CATX-8 antibody, RAB11C antibody, AV012978 antibody, RAB25, member RAS oncogene family L homeolog antibody, RAB25, member RAS oncogene family antibody, RAB25, member RAS oncogene family a antibody, rab25.L antibody, RAB25 antibody, rab25 antibody, rab25a antibody, Rab25 antibody

Background:

Description: Members of the Ras-related superfamily of GTP binding proteins, which includes Ras, Rho, Rab and ARF subfamilies, exhibit 30-50 % similarity with Ras p21. Rab proteins play an important role for either in endocytosis or in biosynthetic protein transport. The possibility that Rab proteins might also direct the exocytosis from secretory vesicles to the plasma membrane is supported by the observation that in yeast, the SEC4 protein, which is 40 % similar to Rab proteins, is associated with secretory vesicles. Rab proteins located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Rab25 was cloned from a gastric parietal cell cDNA library and is expressed in epithelial tissues such as the gastrointestinal mucosae, kidney, and lung, which encoded a protein of 28 kDa.

Aliases: CATX-8, RAB25

Molecular Weight: 24kDa

Gene ID: 57111

HGNC: 57111

UniProt: P57735