MSTN antibody

Catalog No. ABIN969306

Product Details anti-MSTN Antibody

Target: MSTN (Myostatin (MSTN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MSTN antibody is un-conjugated

Application: ELISA

Purpose: Myostatin Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of Myostatin expressed in E. Coli.

Clone: 6H12

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-MSTN antibody (ABIN969306)

Awano, Takeshima, Okizuka, Saiki, Yagi, Matsuo: "Wide ranges of serum myostatin concentrations in Duchenne muscular dystrophy patients." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 391, Issue 1-2, pp. 115-7, (2008) (PubMed).

Wójcik, Nogalska, Engel, Askanas: "Myostatin and its precursor protein are increased in the skeletal muscle of patients with Type-II muscle fibre atrophy." in: Folia morphologica, Vol. 67, Issue 1, pp. 6-12, (2008) (PubMed).

Target Details for MSTN

Target: MSTN (Myostatin (MSTN))

Alternative Name: Myostatin (MSTN Products)

Synonyms: GDF-8 antibody, GDF8 antibody, gdf8 antibody, mstn antibody, zgc:109749 antibody, Gdf8 antibody, NV13143 antibody, MSLHP antibody, Cmpt antibody, myostatin antibody, myostatin b antibody, growth/differentiation factor 8 antibody, MSTN antibody, mstnb antibody, LOC5577632 antibody, BRAFLDRAFT_290840 antibody, Mstn antibody, mstn antibody

Background:

Description: The protein is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.

Aliases: Myostatin, GDF8, MSTN

Molecular Weight: 42.7kDa

Gene ID: 2660

HGNC: 2660

UniProt: O14793