MSH6 antibody
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- Target See all MSH6 Antibodies
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MSH6 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- MSH6 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human MSH6 expressed in E. Coli.
- Clone
- 5B11
- Isotype
- IgG1
- Top Product
- Discover our top product MSH6 Primary Antibody
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
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Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).
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- Target
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- Alternative Name
- MSH6 (MSH6 Products)
- Background
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Description: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. ,
Aliases: GTBP, HSAP, HNPCC5
- Molecular Weight
- 160kDa
- Gene ID
- 2956
- HGNC
- 2956
- UniProt
- P52701
- Pathways
- DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
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