Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

MSH6 antibody

MSH6 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 5B11 unconjugated
Catalog No. ABIN969292
  • Target See all MSH6 Antibodies
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Reactivity
    • 76
    • 34
    • 26
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 57
    • 16
    • 3
    Mouse
    Clonality
    • 44
    • 31
    • 1
    Monoclonal
    Conjugate
    • 44
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MSH6 antibody is un-conjugated
    Application
    • 52
    • 26
    • 26
    • 17
    • 14
    • 13
    • 11
    • 8
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Purpose
    MSH6 Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human MSH6 expressed in E. Coli.
    Clone
    5B11
    Isotype
    IgG1
    Top Product
    Discover our top product MSH6 Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Becker, Creagh, ONeill: "Rab39a binds caspase-1 and is required for caspase-1-dependent interleukin-1beta secretion." in: The Journal of biological chemistry, Vol. 284, Issue 50, pp. 34531-7, (2009) (PubMed).

  • Target
    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
    Alternative Name
    MSH6 (MSH6 Products)
    Background

    Description: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. ,

    Aliases: GTBP, HSAP, HNPCC5

    Molecular Weight
    160kDa
    Gene ID
    2956
    HGNC
    2956
    UniProt
    P52701
    Pathways
    DNA Damage Repair, Chromatin Binding, Production of Molecular Mediator of Immune Response
You are here:
Support