ERK1 antibody
-
- Target See all ERK1 (MAPK3) Antibodies
- ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))
-
Reactivity
- Human
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This ERK1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Purpose
- MAPK3 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human MAPK3 expressed in E. Coli.
- Clone
- 1E5
- Isotype
- IgG1
- Top Product
- Discover our top product MAPK3 Primary Antibody
-
-
- Application Notes
-
ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
C-Raf inhibits MAPK activation and transformation by B-Raf(V600E)." in: Molecular cell, Vol. 36, Issue 3, pp. 477-86, (2009) (PubMed).
: "
-
C-Raf inhibits MAPK activation and transformation by B-Raf(V600E)." in: Molecular cell, Vol. 36, Issue 3, pp. 477-86, (2009) (PubMed).
-
- Target
- ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))
- Alternative Name
- MAPK3 (MAPK3 Products)
- Background
-
Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Aliases: ERK1, PRKM3, P44ERK1, P44MAPK, HS44KDAP, HUMKER1A, MGC20180
- Molecular Weight
- 44kDa
- Gene ID
- 5595
- HGNC
- 5595
- UniProt
- P27361
- Pathways
- MAPK Signaling, RTK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins
-