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MAP2K6 antibody

MAP2K6 Reactivity: Human WB, ELISA, ICC, FACS Host: Mouse Monoclonal 3H12C8 unconjugated
Catalog No. ABIN969269
  • Target See all MAP2K6 Antibodies
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Reactivity
    • 70
    • 63
    • 37
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 87
    • 6
    • 2
    Mouse
    Clonality
    • 89
    • 6
    Monoclonal
    Conjugate
    • 46
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MAP2K6 antibody is un-conjugated
    Application
    • 83
    • 41
    • 27
    • 27
    • 17
    • 14
    • 12
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Purpose
    MAP2K6 Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human MAP2K6 expressed in E. Coli.
    Clone
    3H12C8
    Isotype
    IgG1
    Top Product
    Discover our top product MAP2K6 Primary Antibody
  • Application Notes

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Arning, Monté, Hansen, Wieczorek, Jagiello, Akkad, Andrich, Kraus, Saft, Epplen: "ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 4, pp. 485-90, (2008) (PubMed).

  • Target
    MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))
    Alternative Name
    MAP2K6 (MAP2K6 Products)
    Synonyms
    MAPKK6 antibody, MEK6 antibody, MKK6 antibody, PRKMK6 antibody, SAPKK-3 antibody, SAPKK3 antibody, Mkk6 antibody, Prkmk6 antibody, MKK3 antibody, map2k3 antibody, zMKK3 antibody, map2k6 antibody, mitogen-activated protein kinase kinase 6 antibody, mitogen-activated protein kinase kinase 6 L homeolog antibody, MAP2K6 antibody, Map2k6 antibody, map2k6 antibody, map2k6.L antibody
    Background

    Description: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas .

    Aliases: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, MAP2K6

    Molecular Weight
    38kDa
    Gene ID
    5608
    HGNC
    5608
    UniProt
    P52564
    Pathways
    MAPK Signaling, TLR Signaling, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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