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LSD1 antibody

KDM1A Reactivity: Human WB, ELISA, IHC Host: Mouse Monoclonal 1B2E5 unconjugated
Catalog No. ABIN969264
  • Target See all LSD1 (KDM1A) Antibodies
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    Reactivity
    • 76
    • 36
    • 29
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 59
    • 15
    • 1
    Mouse
    Clonality
    • 59
    • 17
    Monoclonal
    Conjugate
    • 56
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LSD1 antibody is un-conjugated
    Application
    • 68
    • 35
    • 27
    • 21
    • 17
    • 13
    • 13
    • 10
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purpose
    LSD1/AOF2 Antibody
    Purification
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human LSD1 expressed in E. Coli.
    Clone
    1B2E5
    Isotype
    IgG1
    Top Product
    Discover our top product KDM1A Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).

    Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).

  • Target
    LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
    Alternative Name
    LSD1/AOF2 (KDM1A Products)
    Background

    Description: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.

    Aliases: KDM1, LSD1, AOF2

    Molecular Weight
    93kDa
    Gene ID
    23028
    HGNC
    23028
    UniProt
    O60341
    Pathways
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effect
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