LPP antibody

Catalog No. ABIN969263

Product Details anti-LPP Antibody

Target: LPP (Lipoma-preferred partner (LPP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LPP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purpose: LPP Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human LPP expressed in E. Coli.

Clone: 8B3A11

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-LPP antibody (ABIN969263)

von Ahsen, Rogalla, Bullerdiek: "Expression patterns of the LPP-HMGA2 fusion transcript in pulmonary chondroid hamartomas with t(3;12)(q27 approximately 28;q14 approximately 15)." in: Cancer genetics and cytogenetics, Vol. 163, Issue 1, pp. 68-70, (2005) (PubMed).

Zhang, Wolf-Yadlin, Ross, Pappin, Rush, Lauffenburger, White: "Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules." in: Molecular & cellular proteomics : MCP, Vol. 4, Issue 9, pp. 1240-50, (2005) (PubMed).

Target Details for LPP

Target: LPP (Lipoma-preferred partner (LPP))

Alternative Name: LPP (LPP Products)

Background:

Description: LIM domain containing preferred translocation partner in lipoma. The Zyxin family of proteins contains five members, Ajuba, LIMD1, LPP,TRIP6 and Zyxin. LPP (LIM-containing lipoma-preferred partner), a LIM domain-containing scaffolding protein contains three LIM domains at its carboxy terminus, which are preceded by a proline-rich pre-LIM region containing a number of protein interaction domains. LPP, an 80 kDa protein, localizes to sites of cell adhesion, such as focal adhesions and cell-cell contacts,and shuttles to the nucleus where it has transcriptional activation capacity.The human LPP gene maps to chromosomal location 3q28, and preferentially translocates to the HMGIC gene in a subclass of human benign mesenchymal tumors known as lipomas.

Aliases: LPP

Molecular Weight: 66kDa

Gene ID: 4026

HGNC: 4026

UniProt: Q93052