Lp(a) antibody
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- Target
- Lp(a) (Lipoprotein (Lp(a)))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Lp(a) antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Purification
- purified
- Immunogen
- Purified recombinant fragment of LPA (4330-4521) expressed in E. coli.
- Clone
- 8F6A9
- Isotype
- IgG1
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- Application Notes
- ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- 4°C, -20°C for long term storage
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Effect of aspirin on lipoprotein(a) in patients with ischemic stroke." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 16, Issue 5, pp. 220-4, (2007) (PubMed).
: "The LPA gene C93T polymorphism influences plasma lipoprotein(a) levels and is independently associated with susceptibility to peripheral arterial disease." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 387, Issue 1-2, pp. 109-12, (2007) (PubMed).
: "
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Effect of aspirin on lipoprotein(a) in patients with ischemic stroke." in: Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, Vol. 16, Issue 5, pp. 220-4, (2007) (PubMed).
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- Target
- Lp(a) (Lipoprotein (Lp(a)))
- Alternative Name
- LPA
- Background
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Description: LPA: lipoprotein, Lp(a). Apo(a) is the main constituent of lipoprotein(a) (lp(a)). It has serine proteinase activity and is able of autoproteolysis. Inhibits tissue-type plasminogen activator 1.Lp(a) may be a ligand for megalin/gp 330.Apo(a) is known to be proteolytically cleaved, leading to the formation of the so-called mini-lp(a).Apo(a) fragments accumulate in atherosclerotic lesions,where they may promote thrombogenesis.O-glycosylation may limit the extent of proteolytic fragmentation.
Aliases: LP, AK38, APOA, LPA
- Gene ID
- 4018
- HGNC
- 4018
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