KLHL12 antibody
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- Target See all KLHL12 Antibodies
- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This KLHL12 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Purpose
- KLHL12 Antibody
- Purification
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human KLHL12 expressed in E. Coli.
- Clone
- 2G2
- Isotype
- IgG1
- Top Product
- Discover our top product KLHL12 Primary Antibody
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- Application Notes
- ELISA: 1/10000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).
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Ubiquitin-dependent regulation of COPII coat size and function." in: Nature, Vol. 482, Issue 7386, pp. 495-500, (2012) (PubMed).
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- Target
- KLHL12 (Kelch-Like 12 (Drosophila) (KLHL12))
- Alternative Name
- KLHL12 (KLHL12 Products)
- Synonyms
- zgc:92570 antibody, wu:fi60g03 antibody, C3ip1 antibody, C3IP1 antibody, DKIR antibody, hDKIR antibody, Ski2 like RNA helicase antibody, kelch like family member 12 L homeolog antibody, kelch like family member 12 antibody, kelch-like family member 12 antibody, kelch-like 12 antibody, SKIV2L antibody, klhl12.L antibody, KLHL12 antibody, klhl12 antibody, Klhl12 antibody
- Background
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Description: Serves as a substrate-specific adapter for the CUL3-based ubiquitin-protein E3 ligase complex. Negatively regulates the Wnt signaling pathway via the targeted ubiquitination and subsequent proteolysis of DVL3.Tissue specificity: Highly expressed in testis and at lower levels in the submandibular salivary gland.
Aliases: DKIR, C3IP1, FLJ27152, KLHL12
- Molecular Weight
- 63kDa
- Gene ID
- 59349
- HGNC
- 59349
- UniProt
- Q53G59
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