KDM4A antibody

Catalog No. ABIN969230

Product Details anti-KDM4A Antibody

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KDM4A antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Purpose: KDM4A Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human KDM4A expressed in E. Coli.

Clone: 5H1

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-KDM4A antibody (ABIN969230)

Hosseinzadeh Shirzeily, Pasbakhsh, Amidi, Mehrannia, Sobhani: "Comparison of differentiation potential of male mouse adipose tissue and bone marrow derived-mesenchymal stem cells into germ cells." in: Iranian journal of reproductive medicine, Vol. 11, Issue 12, pp. 965-76, (2014) (PubMed).

Chen, Zang, Whetstine, Hong, Davrazou, Kutateladze, Simpson, Mao, Pan, Dai, Hagman, Hansen, Shi, Zhang: "Structural insights into histone demethylation by JMJD2 family members." in: Cell, Vol. 125, Issue 4, pp. 691-702, (2006) (PubMed).

Tao, Wollscheid, OBrien, Eng, Li, Bodenmiller, Watts, Hood, Aebersold: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, (2005) (PubMed).

Suzuki, Yamashita, Shirota, Sakakibara, Chiba, Mizushima-Sugano, Nakai, Sugano: "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions." in: Genome research, Vol. 14, Issue 9, pp. 1711-8, (2004) (PubMed).

Target Details for KDM4A

Target: KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))

Alternative Name: KDM4A (KDM4A Products)

Synonyms: JMJD2A antibody, JHDM3A antibody, JMJD2 antibody, TDRD14A antibody, D4Ertd222e antibody, Jmjd2 antibody, Jmjd2a antibody, mKIAA0677 antibody, lysine demethylase 4A antibody, lysine-specific demethylase 4A antibody, lysine (K)-specific demethylase 4A antibody, KDM4A antibody, LOC100228023 antibody, Kdm4a antibody

Background:

Description: This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

Aliases: JMJD2, JHDM3A, JMJD2A, KIAA0677, KDM4A

Molecular Weight: 120kDa

Gene ID: 9682

HGNC: 9682

UniProt: O75164

Pathways: Warburg Effect